The researched of some aspects of Anopheles dinamics activities in the middle sumba regency has been done in August 2009 where located in region work of Maradesa local clinic. The purpose of the researched were to identify breeding places, density, bitting behaviour and resting behaviour. The collectioned of the samples were done through caught the Anopheline both in indoors and outdoors by night landing collections and night resting collections. And continued with larval surveys in all suspected potential breeding places. The result of the observation was known that breeding place which met in the researched area were consisted of small hole in the ground, small river, rice field, non permanent irrigation, saving water in the kitchen garden, drain, flooded area, swamp, water source with species that met such as An. kochi, An. aconitus, An. tesselatus, An barbtrostris, An. vagus, An. jlavirostris, An. maadatus, An. indefinitus, and An. annullaris. The bitting behaviour of An. kochi; An. oconitus. and An. barbirostris with exophaging with the highest density at An. aconitus (0,6 person/hour) with bitting peak at 08.00-09.00 pm. The resting behaviour were exophilic at An. kochi, An. aconitus, An.tesselatus, An barbirostris, An. vagus, An. flavirostris, An. maculatus and An. indefinitus, . with the highest density in An. aconitus (0,9 person/hour} at 01.00-02.00 am.